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24 March 2014

A Test of Validity of a New Open-Circuit Indirect Calorimeter (Quark RMR validation)

Posted in Quark RMR, Scientific

indirect calorimetry

A new validation study on Quark RMR was published by Pennsylvania State University researchers on the Journal of Parenteral and Enteral Nutrition (JPEN).

A prospective, observational, N-of-1 trial was conducted to validate COSMED Quark RMR, a new-generation indirect calorimeter against Deltatrac, the gold standard device that is no longer manufactured.

The study design was chosen to minimize and define the degree of biological variation, thus focusing on variation due to the devices. Measurements of gas exchange using both indirect calorimeters were conducted daily for 10 consecutive days.

The study concludes that "the Quark RMR was demonstrated to be unbiased, precise, reproducible, and accurate compared with an indirect calorimeter that is regarded as a criterion method but is no longer manufactured. The Quark RMR is a valid instrument for measuring gas exchange in spontaneously breathing people".

The article details are the following:

- Title: "A Test of Validity of a New Open-Circuit Indirect Calorimeter"
- Authors
: Christine M. Ashcraft and David C. Frankenfield - Department of Clinical Nutrition, Department of Nursing, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania
- Published in
:JPEN J Parenter Enteral Nutr. 2014 Mar 10

The scientific article can be purchased at the following link: click here


Founded in 1980, COSMED is a privately owned company manufacturing Cardio Pulmonary and Metabolic Diagnostic Equipment. COSMED products include a full range of Spirometers, Pulmonary Function, Body Composition, Nutritional Assessment and Cardio Pulmonary Exercise systems, including Electrocardiographs, Ergometers and Assessment Software. COSMED solutions are aimed for either professional or medical use for many different applications like: Hospital, Clinics, Primary Care, University & Education in Human Physiology, Clinical Nutrition, Commercial Weight Management, Human Performance Centers, Sport Institutions and Health Club Industry. COSMED Headquarters are located in the province of Rome, Italy. COSMED has subsidiaries in the USA, China and Germany, and distributes its products internationally through a constantly growing distributor network covering more than 70 countries.