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Scientific News

A selection of scientific articles on Cardio Pulmonary, Lung Function, Metabolism and Body Composition

The Role of Gas Exchange Variables in Cardiopulmonary Exercise Testing for Risk Stratification and Management of Heart Failure with Reduced Ejection Fraction

25 April 2018
A scientific review was made in the American Heart Journal examining 5 major gas exchange variables from CPET in heart failure with reduced ejection fraction (HFrEF) patients. The purpose of this review is to examine the role of cardiopulmonary exercise testing (CPET) and its most commonly used ventilatory gas exchange variables for the purpose o…

Reference values for peak oxygen uptake: cross-sectional analysis of cycle ergometry-based cardiopulmonary exercise tests of 10 090 adult German volunteers from the Prevention First Registry

01 March 2018
A recent study presented new reference values for peak oxygen uptake for cycle ergometry-based cardiopulmonary exercise test. The goal of the present analysis was to generate sex-specific and age-specific reference values for cycle ergometry-based V̇ O2peak, based on a sample of more than 10000 participants from primary preventive healthcare chec…

New Reference Values for Cardiopulmonary Exercise Testing in Children

26 January 2018
A new study on Medicine & Science in Sports & Exercise (MSSE) Journal provides updated reference values for CPET that are independent of sex and body size. Cardiopulmonary exercise testing (CPET) is an essential tool to assess cardiorespiratory fitness (CRF) in children. There is a paucity of adequate pediatric reference values that are i…

The Maximal Oxygen Uptake Verification Phase: a Light at the End of the Tunnel?

26 January 2018
The verification phase of the VO2max assessment has been investigated in this paper published on the Sports Medicine - Open Journal. Commonly performed during an incremental test to exhaustion, maximal oxygen uptake (V̇O2max) assessment has become a recurring practice in clinical and experimental settings. To validate the test, several criteria w…

A practical clinical approach to utilize cardiopulmonary exercise testing in the evaluation and management of coronary artery disease: a primer for cardiologists

19 December 2017
A new review on the Current Opinion on Cardiiology Journal addresses the clinical approach to utilize CPET in the evaluation and management of coronary artery disease (CAD). There is growing clinical interest for the use of cardiopulmonary exercise testing (CPET) to evaluate patients with or suspected coronary artery disease (CAD). With mounting…

Repeatability and Meaningful Change of CPET Parameters in Normal Subjects

06 December 2017
A new study on Medicine & Science in Sports & Exercise (MSSE) Journal investigates the repeatability of CPET parameters in normal healthy subjects. Cardiopulmonary exercise testing (CPET) has many important clinical and research applications. Defining repeatability of CPET measurements is important when determining a response to a therapy…

Open-circuit respirometry: a historical review of portable gas analysis systems

13 October 2017
The European Journal of Applied Physiology is publishing a series of reviews examining some historical insights into the measurement of whole body metabolic rate. This review is focusing on portable research based devices designed to estimate metabolic rates during typically steady-state conditions, and areas that contribute to measurement errors…

Role of cardiopulmonary exercise testing in clinical stratification in heart failure. A position paper from ESC

26 September 2017
A new position paper on CPET from the Committee on Exercise Physiology and Training of the Heart Failure Association of the European Society of Cardiology was published in the European Journal of Heart Failure. The aim of the present paper is to review the prognostic role of CPET in Heart Failure (HF) considering the individual patient characteri…

Cardiopulmonary exercise testing and second-line pulmonary function tests to detect obstructive pattern in symptomatic smokers with borderline spirometry

27 June 2017
A study published on the Respiratory Medicine Journal investigates the need for additional research on smokers with respiratory symptoms (dyspnoea, cough, or sputum production) and normal spirometry. The purpose of this study was to evaulate whether symptomatic smokers with borderline spirometry (post-bronchodilator FEV1/FVC ratio between 5th to…

Cardiopulmonary exercise factors predict survival in patients with advanced interstitial lung disease referred for lung transplantation

23 June 2017
The Respiratory Medicine Journal presents a new study demonstrating the prognostic value of CPET test parameters as pre-assessment tool for lung transplant ILD patients. The purpose of this work was to determine if parameters assessed during Cardiopulmonary Exercise Testing (CPET) while using supplemental oxygen can independently predict one-year…

Systematic review: pre- and post-operative prognostic value of cardiopulmonary exercise testing in liver transplant candidates

12 May 2017
Interesting literature review on the Alimentary Pharmacology and Therapeutic Journal focusing on the role of cardio pulmonary exercise test (CPET) in cirrhosis patients. The prognostic value of CPET for pre-and post-transplant mortality is evaluated in patients with cirrhosis listed for liver transplantation. In particular, this review analyses w…

Cardiopulmonary exercise testing for detecting pulmonary arterial hypertension in systemic sclerosis

24 March 2017
This study published on the Heart Journal analyses the diagnostic role of cardiopulmonary exercise test for detecting and ruling of systemic sclerosis pulmonary arterial hypertension (SSC-associated PAH). Pulmonary arterial hypertension (PAH) is a devastating disease with limited survival and occurs as a frequent complication in patients with sys…

The correlation of respiratory muscle strength and cough capacity in stroke patients

14 March 2017
A study on the Journal of Physical Therapy Science investigates how inspiratory and expiratory training can improve cough capacity in stroke patients, which can reduce pulmonary complications. The purpose of this study was to investigate the correlation between respiratory muscle strength improvement through respiratory training and cough capacit…

CORP: Measurement of the Maximum Oxygen Uptake (VO2max): VO2peak is no longer acceptable

10 March 2017
A new paper on the Journal of Applied Physiology examines the so-called secondary criteria used to validate VO2max iin particular with exercise naïve, unmotivated and/or clinical populations. This article is part of the new Cores of Reproducibility in Physiology (CORP), an American Physiology Society(APS)-wide initiative responsive to a growing c…

Pediatric Exercise Testing: Value and Implications of Peak Oxygen Uptake

30 January 2017
A new essay published on Children Jornal highlights the clinical relevance of cardiopulmonary exercise testing. Much of what is known about exercise physiology has been derived from studies done in adults, yet every pediatrician knows that lessons learned from research in adults do not necessarily apply to children or even to adolescents. There i…

Cardiopulmonary exercise testing is a better outcome predictor than exercise echocardiography in asymptomatic aortic stenosis

20 January 2017
The International Journal of Cardiology hosts a paper confirming the validity of Cardiopulmonary Exercise Testing on patients with asymptomatic aortic stenosis. The assessment of maximal aerobic capacity using peak oxygen consumption (peak VO2) can be helpful in the management of patients with asymptomatic aortic stenosis (AS). This study explore…

Within and between-day reliability of energetic cost measures during treadmill walking

29 December 2016
This study published in Cogent Engineering Journal analyses the capacity of COSMED K4b2 portable metabolic system in detecting small physiologic changes within a day on healthy adults. The efficacy of assistive devices used during walking is often measured as a reduction in metabolic cost. Metabolic cost is typically assessed within a day or on m…

A systematic review and meta-analysis comparing cardiopulmonary exercise test values obtained from the arm cycle and the leg cycle respectively in healthy adults

28 December 2016
This new paper reviews results of previous studies in comparing cardio pulmonary exercise test results achieved by arm cycle ergometer (AC) and to leg cycle ergometer (LC) Despite most of the CPET tests are performed using a treadmill or a leg cycle ergometer, due to disability, co-morbidity, preference or athletic discipline there is a need to i…

Prognostic value of cardiopulmonary exercise testing in Idiopathic Dilated Cardiomyopathy

21 December 2016
The prognostic value of CPET in Idiopathic Dilated Cardiomyopathy (iDCM) patients has been studies in a recent paper published in the International Journal of Cardiology. Although cardiopulmonary exercise testing (CPET) is considered as an important tool in risk stratification of patients with heart failure (HF), prognostic data in the specific s…

Assessment of human energy exchange: historical overview

13 December 2016
A recent paper on the European Journal of Clinical Nutrition provides a conceptual historical framework for examining the evolution of energy exchange concepts and measurement methods. Energy exchange is fundamental to life and is a cornerstone in the study of human physiology, metabolism and nutrition. A global effort is underway to further our…

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