Premature infants often undergo postnatal growth failure and show an altered body composition (BC) at termequivalent age (TEA) with lower fat-free mass (FFM) and increased fat mass (FM) than infants born at term. Early nutrition and growth may impact brain growth. Nevertheless, the evidence relating BC and later neurodevelopment remains sparse. The aim of this study is to evaluate whether in...
Body composition is a sensitive marker of infants’ intra- and extrauterine growth quality that can influence short- and long-term outcomes; including retinopathy of prematurity, bronchopulmonary dysplasia (BPD), metabolic health, cardiovascular and neurodevelopmental outcomes. Low body fat percentage at birth in small and appropriate for gestational age infants is a marker of undernutrition...
The study wants to explore the longitudinal association of neonatal adiposity (fat mass percentage) with BMI trajectories and childhood overweight and obesity from ages 2 to 6 years. METHODS: We studied 979 children from the Healthy Start cohort. Air displacement plethysmography was used to estimate fat mass percentage. Child weight and recumbent length or standing height were abstracted...
Chronic kidney disease (CKD) is characterized by accelerated aging, but the age-related changes in body composition and its modification by sex and race are unclear. METHODS: We assembled a cohort of 516 patients with CKD and 45 healthy controls and serially measured body composition using air-displacement plethysmography for up to 6 years. Mixed models were used to evaluate simultaneously...
In this study, only the change in FM% in the first 6 months of life was associated with more adiposity at age 2 years. Infants with a rapid increase in FM% had higher trajectories of FM% and FM index during the first 2 years of life. These findings appear to support a critical window for adiposity programming in early life. Question Is a rapid increase in fat mass percentage in early life...
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