Cardiopulmonary exercise factors predict survival in patients with advanced interstitial lung disease referred for lung transplantation
The Respiratory Medicine Journal presents a new study demonstrating the prognostic value of CPET test parameters as pre-assessment tool for lung transplant ILD patients.
The purpose of this work was to determine if parameters assessed during Cardiopulmonary Exercise Testing (CPET) while using supplemental oxygen can independently predict one-year transplant- free survival in patients with Interstitial Lung Disease (ILD) referred for lung transplant evaluation.
The study comprised a chart review of patients with ILD who completed CPET with 30% FiO2 and gathered spirometry, pulmonary hemodynamic, six-minute walk, and CPET data. The primary end-point was death or lung transplantation within one-year of CPET.
The findings of this research "demonstrate the potential of added prognostic value in measuring peak workload and nadir SpO2 by CPET to identify patients who have an increased likelihood of clinical deterioration and death".
The article details are the following:
- Title: "Cardiopulmonary exercise factors predict survival in patients with advanced interstitial lung disease referred for lung transplantation"
- Authors: Layton AM, Armstrong HF, Kim HP, Meza KS, D'Ovidio F, Arcasoy SM
- Published in: Respir Med. 2017 May;126:59-67
The study can be purchased at the following link: click here
