The effect of indirect calorimetry guided isocaloric nutrition on mortality in critically ill patients—a systematic review and meta-analysis

Indirect calorimetry (IC)-guided nutrition might positively affect the clinical outcome of critically ill patients. The objective of this study is to assess the benefit of isocaloric nutrition guided by IC, compared to hypocaloric nutrition, for critically ill patients admitted to the intensive care unit (ICU).

This systematic review and meta-analysis shows that patients treated with IC guided isocaloric nutrition had a lower 28-day all-cause mortality in comparison to patients treated with hypocaloric nutrition. However, there was no difference in long-term mortality and nosocomial infection rate.

Measuring energy expenditure remains the first step to evaluate the ICU patient’s nutritional needs.

Further studies evaluating the effect of specific administered/measured REE ratios may give the answer regarding the amount of energy to administer to critically ill patients.

 
Article details:

- Title: The effect of indirect calorimetry guided isocaloric nutrition on mortality in critically ill patients—a systematic review and meta-analysis
- Authors: Barak Pertzov, Haggai Bar-Yoseph, Yehonatan Menndel, Itai Bendavid, Ilya Kagan, Yehuda Daniel Glass & Pierre Singer
- Published in: European Journal of Clinical Nutrition - 15 June 2021
- Link: https://doi.org/10.1038/s41430-021-00919-0