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Scientific News

A selection of scientific articles on Cardio Pulmonary, Lung Function, Metabolism and Body Composition

Prognostic value of cardiopulmonary exercise testing in Idiopathic Dilated Cardiomyopathy

21 December 2016
The prognostic value of CPET in Idiopathic Dilated Cardiomyopathy (iDCM) patients has been studies in a recent paper published in the International Journal of Cardiology. Although cardiopulmonary exercise testing (CPET) is considered as an important tool in risk stratification of patients with heart failure (HF), prognostic data in the specific...

Assessment of human energy exchange: historical overview

13 December 2016
A recent paper on the European Journal of Clinical Nutrition provides a conceptual historical framework for examining the evolution of energy exchange concepts and measurement methods. Energy exchange is fundamental to life and is a cornerstone in the study of human physiology, metabolism and nutrition. A global effort is underway to further ou...

Airflow obstruction: is it asthma or is it COPD?

13 December 2016
An interesting study in the International Journal Chronic Obstructive Pulmonary Disease traces the difficulties to differentiate asthma from COPD. Despite the availability of guideline recommendations, diagnostic confusion between COPD and asthma appears common, and often it is very difficult in a patient with airway obstruction to decide wheth...

Indirect calorimetry: an indispensable tool to understand and predict obesity

01 December 2016
The European Journal of Clinical Nutrition hosts a new study, which summarizes recent research on the importance of indirect calorimetry in predicting weight gain and obesity. The study reviewed data from indirect calorimetry key metabolic predictors (resting metabolic rate, spontaneous physical activity and respiratory quotient) to gain insigh...

Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign

01 December 2016
A new statement by the American Heart Association has been recently published suggesting the addition of cardiorespiratory fitness (CRF) for risk classification in patient management and to encourage strategies designed to reduce cardiovascular risk. The purpose of this statement was to review current knowledge related to the association betwee...

New body composition reference charts for preterm infants

09 November 2016
An extremely important study has been published in the American Journal of Clinical Nutrition providing body composition reference curves for preterm infants. The objective of this study was to create ADP-based body composition reference curves for preterm infants that approximate, as close as is feasible in live-born infants near birth, the bo...

Influence of different dialysis modalities in the measurement of resting energy expenditure in patients with acute kidney injury in ICU

20 October 2016
A new prospective cohort study published on ESPEN's Clinical Nutrition Journal evaluated the role and the feasibility of indirect calorimetry (IC) among patients admitted in intensive care units with diagnosis of acute kidney injury (AKI). A key issue on these patients is that general recommendations suggest to not perform IC during dialysis, b...

Estimating fat mass in heart failure patients

20 October 2016
New research from the Charité Universitätsmedizin Berlin presents an explorative, single-centre, observational, study assessing body composition (BC) in heart failure (HF) patients using a multi-method, two-compartment approach. The aim of the present study is to assess the association of simple anthropometric indices such as BMI and WHR with F...

Strength Training for Adolescents with cerebral palsy (STAR): study protocol of a randomised controlled trial to determine the feasibility, acceptability and efficacy of resistance training for adolescents with cerebral palsy

14 October 2016
A paper published in the British Medical Journal introduces purposes and methodology of a new clinical trial on gait inefficiencies on cerebral palsy adolescents that will be using COSMED wearable metabolic technology. A multicentre randomised controlled trial with a parallel process evaluation is going to be sponsored by Burnel University Lond...

Preterm infant body composition cannot be accurately determined by weight and length

05 October 2016
A new study determines, using ADP as a validation method, whether any of the anthropometric indices used historically or currently accurately predict body composition in infants. Body composition is a key metric for assessing nutrition in preterm infants. In many neonatal intensive care units body composition is estimated using anthropometric i...

Maximal aerobic capacity in ageing subjects: actual measurements versus predicted values

03 October 2016
A new study in the European Respiratory Journal focuses on proper interpretation values for the measured VO2max in elderly patients. This study stresses the importance of the selection of VO2max reference equations, especially for older subjects, and offers clinicians some information to guide their choice. As a matter of fact, predicted VO2max...

Single-breath washout tests to assess small airway disease in COPD

03 October 2016
A new paper published on Chest Journal investigated the role of Single Breath Nitrogen Washout (N2WO) as a marker to evaluate small airway disease in COPD patients. Given that current functional assessments do not allow a reliable assessment of small airways, One of the major causes of disease in COPD comes from small airways, which could not b...

Poor Agreement between Predictive Equations of Energy Expenditure and Measured Energy Expenditure in Critically Ill Acute Kidney Injury Patients

03 October 2016
The reliability of predictive equations versus indirect calorimetry in kidney injury patients has been assessed in this paper published in Annals of Nutrition and Metabolism Journal. There are multiple equations for predicting resting energy expenditure (REE), whose accuracy in severe acute kidney injury (AKI) patients has been examined in this...

Evolving Role of Exercise Testing in Contemporary Cardiac Rehabilitation

15 September 2016
The utility of graded exercise tests, cardiopulmonary exercise tests, submaximal walking tests, and other functional assessments (strength, frailty) for Cardiac Rehabilitation have been reviewed in this article of the Journal of Cardiac Rehabilitation and Prevention. This review addresses the role and optimal use of exercise testing in contempo...

VO2Max and VO2AT: athletic performance and field role of elite soccer players

13 September 2016
The findings of a 12-year research period on elite football professional athletes were published in the Italian journal "Sport Sciences for Health". The aim of the research, conducted by the team of Italian sport scientist Danilo Manari, was to study the relations of maximal oxygen consumption (VO2max) and oxygen consumption at anaerobic thresh...

Oxygen Uptake Efficiency Slope, an Objective Submaximal Parameter in Evaluating Exercise Capacity in Pulmonary Thromboembolism

06 September 2016
A new study was published in the American Journal of Medical Sciences highlighting the importance of a submaximal exercise parameter, the OUES, to identify exercise capacity of pulmonary thromboembolism (PE) patients. The objective of this article was to study the oxygen uptake efficiency, an index of cardiopulmonary functional reserve that can...

Feasibility and Acceptability of Implementing Indirect Calorimetry Into Routine Clinical Care of Patients With Spinal Cord Injury

06 September 2016
A new paper tested how acceptable can be among spinal cord injury patients to undertake an indirect calorimetry test with canopy hood. In the absence of reliable predictive equations, indirect calorimetry (IC) remains the gold standard for assessing energy requirements after spinal cord injury (SCI), but it is typically confined to a research s...

Analysis of the body composition of Paralympic athletes: Comparison of two methods

06 September 2016
The ECSS Journal (EJSS, European Journal of Sport Science) published a new article examining the best methods to measure body composition on paralympic athletes. The study objectives were to describe the body composition of participants in three distinct Paralympic sports and to compare the values of body density and estimated body fat obtained...

Reference Standards for Cardiorespiratory Fitness Measured With Cardiopulmonary Exercise Testing

18 August 2016
The Mayo Clinic Procedures Journal hosts an article describing the project to create a registry of cardiorespiratory fitness (CRF) reference values. Given the importance of CRF in estimating health risk, it is essential to have accurate reference values to know what constitutes a “normal” value. In 2014, a multi-institutional initiative, the Fi...

Abbreviated Steady State Intervals for Measuring Resting Energy Expenditure in Patients on Maintenance Hemodialysis

18 August 2016
A new cross-sectional secondary analysis was published in the Journal of Parenteral and Enteral Nutrition (JPEN) focusing on issue related to the indirect calorimetry test in hemodialysis patients. Indirect calorimetry requires a steady state (SS) protocol to determine measured resting energy expenditure (mREE). Achieving stringent criteria for...

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